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ALDHAldehyde Dehydrogenase
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Overexpression of a stress-inducible aldehyde dehydrogenase gene from Arabidopsis thaliana in transgenic plants improves stress tolerance.
Abbreviations: ACE: angiotensin-converting enzyme; ACh: acetylcholine; ALDH2: aldehyde dehydrogenase 2; ARB: angiotensin II receptor blocker; CAS: coronary artery spasm; CCB: calcium-channel blocker; ECG: electrocardiogram; e-NOS: endothelial nitric oxide synthase; hsCRP: high-sensitivity C-reactive protein; ISDN: isosorbide dinitrate; LDL: low-density lipoprotein; L-NMMA: L-monomethyl-arginine; MI: myocardial infarction; MLC: myosin light chain; MLCK: myosin light chain kinase; MLCP: myosin light chain phosphatase; NO: nitric oxide; NOS: nitric oxide synthase; PCI: percutaneous coronary intervention; ROCK: Rho-associated kinase; ROS: reactive oxygen species.
Aldehyde dehydrogenase is essential for both adult and larval ethanol resistance in Drosophila melanogaster.
[2] Nonstandard abbreviations: CTCs, circulating tumor cells; ALDH, aldehyde dehydrogenase; EpCAM, epithelial cell adhesion molecule; MET, mesenchymal-epithelial transition; NSCLC, non-small cell lung cancer; TERT, telomerase reverse transcriptase.
Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-Acetyl-1-pyrroline, a major component in rice fragrance.
Distinct hematopoietic progenitor compartments are delinated by the expression of aldehyde dehydrogenase and CD34.
It is caused by deficient activity of fatty aldehyde dehydrogenase (FALDH), a component of the fatty alcohol nicotinamide adenine dinucleotide (NAD) oxidoreductase enzyme complex (FAO).
Betts, "Kinetics and reaction mechanism of potassium-activated aldehyde dehydrogenase from Saccharomyces cerevisiae," Biochemical Journal, vol.
Background: Aldehyde dehydrogenase 2 (ALDH2) is involved in the pathophysiological processes of cardiovascular diseases.
The pathogenesis of coronary artery disease occurs over a long period of time, involves many environmental and lifestyle factors, including hypertension, hyperlipaemia, diabetes, tobacco smoking, obesity and family history of atherosclerosis.2,3 Additionally, hereditary factors play an important role in the risk of coronary artery disease susceptibility, and previous published studies have revealed that many genetic factors play an important role in the development of this diseases, such as B-cell lymphoma 2 2, aldehyde dehydrogenase 2, cholesterylester transfer protein, interleukin-10 (IL-10) and scavenger receptor class B type 1.4-9
Gene variants encoding several of the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest genetic associations with risk for alcohol dependence.
(7) Metronidazole did not have any inhibitory effect on hepatic or colonic alcohol dehydrogenase or aldehyde dehydrogenase. What was found was that rats treated with metronidazole had increased growth of Enterobacteriaceae, an alcohol dehydrogenase-containing aerobe, which could be the cause of the higher intracolonic acetaldehyde levels.
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