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Worldwide racial and ethnic distribution of alpha-1-antitrypsin deficiency: details of an analysis of published genetic epidemiological surveys.
Evaluation of an integrative diagnostic algorithm for the identification of people at risk for alpha-1-antitrypsin deficiency.
Intestinal Wegener's granulomatosis in a patient with severe alpha-1-antitrypsin deficiency resulting from a unique combination of two deficiency alleles (PiZ and PiMProcida).
Severe Alpha-1-Antitrypsin Deficiency, also known as AAT Deficiency or Alpha-1, is an inherited disorder that causes a significant reduction of the serum concentration of the naturally occurring protein AAT.
Amino acid substitution Glu-Lys in alpha-1-antitrypsin PiZ.
Grant programs such as the Talecris Biotherapeutics Alpha-1 Research Initiative and the European Alpha-1-Antitrypsin Laurell's Training Award (eALTA), which support basic and clinical research and education through grants provided to early career investigators, fellows-in-training, and other Alpha-1 health care professionals, are continuing.
Infusion of alpha-1-antitrypsin (ATT) to suppress Human Immunodeficiency Virus Type 1 (HIV) replication in patients:
Koczulla's project, "Quantification of Alpha-1-Antitrypsin in Exhaled Breath Condensate of Patients with Alpha-1-Antitrypsin Deficiency, Smokers, and COPD Patients," intends to create a non-invasive tool to measure Alpha-1-Antitrypsin levels, examine correlations with markers of pulmonary inflammation, and ultimately help guide disease therapy.
Alpha-1 is a form of congenital emphysema that causes degradation of a patient's lung tissue due to inadequate production of alpha-1-antitrypsin (AAT).
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