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ALHEAngiolymphoid Hyperplasia with Eosinophilia
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Angiolymphoid Hyperplasia with Eosinophilia (ALHE) is a rare benign, vasoproliferative entity of unknown etiology.
Table 1: Distinguishing clinicopathological features of Angiolymphoid Hyperplasia with Eosinophilia and Kimura Disease.
Angiolymphoid hyperplasia with eosinophilia (AHE) was first described in 1969 by Wells and Whimster.
The term angiolymphoid hyperplasia with eosinophilia (ALHE) was coined by Wells and Whimster (1) in 1969 to describe a distinct neoplasm characterized by a florid proliferation of blood vessels lined by plump endothelial cells and admixed with a dense inflammatory infiltrate of lymphocytes, eosinophils, and mast cells.
Kimura's disease and angiolymphoid hyperplasia with eosinophilia: two entities in the same patient: case report and review of the literature.
INTRODUCTION: Angiolymphoid hyperplasia with eosinophilia is an uncommon, idiopathic, benign, but potentially disfiguring vascular lesion which usually occurs during early and mid adult life (1, 2).
Angiolymphoid hyperplasia with eosinophilia and vascular tumors of the head and neck.
Kimura disease is sometimes confused with angiolymphoid hyperplasia with eosinophilia, Hodgkin lymphoma, angioimmunoblastic T-cell lymphoma, florid follicular hyperplasia, Castleman disease, and lymphadenopathy secondary to drug reactions and parasitic infections.
Angiolymphoid hyperplasia with eosinophilia (ALHE), characterized by dermal and subcutaneous nodules in head and neck areas, is often very disfiguring.
Kimura's disease can also be confused with angiolymphoid hyperplasia with eosinophilia (ALHE).