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ARRAnnual Recurring Requirement
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ARRAnnual Results Report (various organizations)
ARRActive Rebuilders and Restorers
ARRArkansas Rides (automotive enthusiast forum)
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References in periodicals archive ?
Both studies met the primary endpoints where ofatumumab showed a highly significant and clinically meaningful reduction in the number of confirmed relapses, evaluated as the annualized relapse rate (ARR)[1].
Both studies met the primary endpoints where ofatumumab showed a highly significant and clinically meaningful reduction in the number of confirmed relapses, evaluated as the annualized relapse rate. Key secondary endpoints of delaying time to confirmed disability progression were also met.
Compared with nonoverweight patients, obese patients had statistically significantly more relapses on first-line treatment with interferon beta and glatiramer acetate (annualized relapse rate, 1.29 versus 0.72) and a higher rate of second-line treatment (56.8 versus 38.7 percent).
New results in 696 MS patients on diroximel fumarate showed a significant reduction in the annualized relapse rate (ARR) by 79 percent over one year when compared to baseline, and by 82 percent in newly diagnosed patients.
Ocrelizumab was shown to be effective and safe in two phase III trials conducted in RRMS patients with a significant reduction in annualized relapse rate (ARR), which confirmed disability progression and new MRI lesions [5].
In a review of 139 Japanese women with NMOSD, the study authors noted an increased annualized relapse rate (ARR) during the first three months postpartum compared to pre-pregnancy; however, the ARR was not reduced during pregnancy [8].
It is the first and only oral short-course treatment to provide efficacy across key measures, including disability progression, annualized relapse rate and magnetic resonance imaging (MRI) activity.
Celgene's Phase III SUNBEAM trial, evaluating the efficacy and safety of ozanimod, an investigational oral, selective S1P 1 and 5 receptor modulator, in patients with relapsing multiple sclerosis (RMS), met the primary endpoint in reducing annualized relapse rate (ARR), compared to weekly interferon (IFN) [beta]-1a (Avonex).
The mean age of these patients was 43 years (SD: 12); the mean duration of the disease 11.6 years (SD: 8.8); the mean expanded disability status scale is 4.1 (SD: 1.9); and the annualized relapse rate is 2.9 (SD: 1.7).
In those of African descent, the cumulative 0- to 5-year annualized relapse rate was 0.16.
Comparison of the various parameters between patients divided into two groups according to the continuation of the immunmodulatory treatment Group 1 Group 2 Annualized relapse rate .68 [+ or -] .82 .61 [+ or -] .46 BDI score 12.84 [+ or -] 9.55 13.24 [+ or -] 9.85 PASAT score .62 [+ or -] .22 .64 [+ or -] .27 EDSS score 2.52 [+ or -] 1.57 3.98 [+ or -] 2.30 Mean age (years) 39.99 [+ or -] 10.2 42.90 [+ or -] 10.69 Education period (years) 9.48 [+ or -] 4.05 9.19 [+ or -] 4.24 Disease duration (years) 10.24 [+ or -] 6.04 12.40 [+ or -] 6.20 p Annualized relapse rate .57 BDI score .88 PASAT score .2 EDSS score <.0001 * Mean age (years) .08 Education period (years) .65 Disease duration (years) .03 * Group 1: under treatment, Group 2: discontinued the treatment.