The effect of testicular trauma on formation of antisperm antibodies
and secondary subfertility in stallions is not known.
Chapter 31 presents the current detection and management of antisperm antibodies
(ASA) as a cause for male infertility including different methods used for detection, testing and treatment.
The impact of antisperm antibodies
on human infertility.
Antisperm antibodies (mixed agglutination reaction)
Antisperm antibodies are almost exclusively IgG and IgA, with the latter clinically more important.3 Depending on the nature and location of the sperm antigen and the levels of antibodies different effects may be seen, as agglutination of sperm with impaired motility and cytotoxicity with low viability are all effects that may adversely affect sperm quality.
Conclusion: Direct correlation of circulating antisperm antibodies with male infertility suggests the role of immunologic infertility as an etiologic cause of infertility in idiopathic infertile males of Pakistan.
Immunologic factors are one of the several mechanisms proposed for male infertility.3 Although advancements of contemporary molecular medicine and diagnostic tools have helped a great deal in understanding the etiology of male infertility during the last two decades but the exact mechanism involved in the pathogenicity of male infertility by Immunologic factors particularly Antisperm Antibodies (ASA) is still poorly understood.
Women don't generally produce antibodies against sperm; however, some infertile women have been found to possess antisperm antibodies, which may contribute to their infertility (12).
trachomatis infection, or the level of antisperm antibodies in asymptomatic Egyptian females with unexplained infertility.
Prevalence of antisperm antibodies
by SpermMARtest in subjects undergoing a routine sperm analysis for infertility.
Serum antisperm antibodies
were detected by indirect immunofluorescence test (EURO IMMUNE, Germany).
can cause sperm agglutination, which results in poor motlity and progression.