Aqp0Aquaporin0 (membrane channel protein found in the lenses of the eye)
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Until recently, the mammalian complement of aquaporins was thought to consist of up to thirteen classes or subfamilies (AQP0 to -12) (King et al., 2004; Kruse et al., 2006; Gomes et al., 2009; Ishibashi et al., 2009).
More than twice that number (17, aqp0 to -16) have been identified in the genomes of different jawed vertebrates (Gnathostomata) (Finn et al., 2014).
Interestingly, at least one set of the lamprey genes (aqp 10L1 and -10L2) appears to have arisen via tandem duplication, while another may have arisen as two separate genes (aqp0 and -1) that subsequently fused (aqp01) (Finn et al., 2014).
This would be the case regardless of the mechanism of gene duplication, i.e., WGD or tandem duplication, which might be inferred from their linkage to aqp0 genes in the chromosomes of many vertebrates.
The pH sensitivity of Aqp0 channels in tetraploid and diploid teleosts.
Cuadro 1 Caracteristicas principales particulares de las 11 acuaporinas conocidas, incluyendo su localizacion y las enfermedades con las cuales se ha definido una asociacion Tipo de Particularidades Localizacion acuaporina AQP0 Funcion estructural Cristalino intercelular AQP1 Expresion poco selectiva Eritrocitos TPR (m.
Both species have partial or complete copies of Aqp0, -1, -4, -9, -10, -12, -14, and -15 and two copies of Aqp3.
aqp0, -1, and -9 all show RT-PCR amplification in gill tissue samples (Fig.
aqp0, -1, and -9 cDNAs all amplify from renal tissue samples using RT-PCR (Fig.
RT-PCR studies also show amplification of aqp0 and very low levels of aqp3 (Fig.
AQP0 is found in the epididymis of the stallion but not in the rat, whereas AQP1 is found in the bat and rat myoid cells surrounding the epididymal tubules of the caput region and endothelial cells of the vascular channels throughout the epididymis, but is not found in the mouse.
However, it is still possible that other Aqp0 and -8 paralogs, such as Aqp0b and -8aa, the latter being phylogenetically closer to the tetrapod AQP8 than to Aqp8b (Cerda and Finn, 2010), are present in seabream somatic cells.