It also reduced pulse wave velocity and augmentation index
For the current study, artery ageing/hardening was assessed in 597 participants using three indices: the peripheral augmentation index
, evaluated by tonometry, and the cardio-ankle vascular index and pulse wave velocity measured by oscillometry.
Mobil-O-Graph ambulatory blood pressure monitor device, which automatically measure pulse wave velocity (PWV), central blood pressure (cBP), augmentation index
(Aix), and central pulse pressure (cPP), was used to evaluate arterial stiffness.
Neubauer et al., "Augmentation index
and pulse wave velocity in normotensive and preeclamptic pregnancies," Acta Obstetricia et Gynecologica Scandinavica, vol.
(AIx) is computed using the algorithm below:
and Blood Pressure Measurements.
This technique also provides calculation of augmentation index
which is an indicator of central arterial stiffness.
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; TC: total plasma cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Scr: serum creatinine; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CK: creatine kinase; CCB: calcium channel blocker; [beta]-B: [beta]blocker; ACEI: angiotensin converting enzyme inhibitor; [beta]: stiffness parameter; Ep: pressure strain elasticity modulus; AC: arterial compliance; AI: augmentation index
; PWV[beta]: one point pulse wave velocity.
Between these two Nexfin measurements, the pulse wave velocity and augmentation index
profiles in the supine position was estimated using the Arteriograph (TensioMed, Budapest, Hungary) (16).
Takazawa, "Augmentation index
in heart disease," American Journal of Hypertension, vol.
found a significant decrease in augmentation index
after 100,000 IU of vitamin D3 (the high-dose group) for 8 weeks, in older adults with vitamin D deficiency .
 emphasised the direct relationship between amplification and augmentation based on their findings that the late systolic shoulder of peripheral pressure waveform closely approximates central systolic pressure and that the peripheral augmentation index
was related to central systolic pressure.