Patients who produce Intrinsic Factor but who then also produce autoimmune Intrinsic Factor Antibodies are diagnosed as having Pernicious Anaemia or more correctly Autoimmune Metaplastic Atrophic Gastritis
. If their condition was not diagnosed early and nerve damage has resulted, then the patient will be diagnosed as having Sub-Acute Combined Degeneration of the Cord Secondary to Pernicious Anaemia.
The anemia may be attributable to decreased iron absorption secondary to hypochlorhydria or achlorhydria, blood loss, or vitamin [B.sub.12] deficiency in the setting of autoimmune metaplastic atrophic gastritis. (7,8)
(4) In addition to an association with autoimmune metaplastic atrophic gastritis, (7,8) PGAs have also been observed in the setting of Helicobacter pylori gastritis and chemical gastritis.