was measured on presentation as the initial B-hCG
, it ranged from 4445 to 142940 mIU/L, it did not add value to the diagnosis, but was in follow up of treatment success.
Her physician gave injection methotrexate, and B-HCG
was performed to see any abnormalities.
* If serum B-HCG
level does not decline up to 15% from day 4 to day 7.
The serum b-hCG
was elevated to 1668mIU/ml (normal < 10 mIU/ml).
In this study, [beta]-hCG are predominantly produced by syncytiotrophoblast and they can be also detected in the differentiating cytotrophoblast.As preeclampsia is probably a trophoblastic disorder, elevated b-hCG
is thought to reflect early placental damage or dysfunction.
Although the urine b-HCG
was negative, her serum b-HCG
was 80.4 (0-5 mIU/mL).
Patients having incomplete history and without b-HCG
levels were excluded.
There are two clear categories of hCG test: 1) intact hCG tests which are designed to detect the intact dimer only; while 2) total hCG tests (most commonly used in commercial laboratories)--also known as B-hCG
tests--are designed to detect the dimer, as well as the free [beta]-subunit, and possibly nicked and other variants of hCG.
El diagnostico de esta patologia representa un reto para el medico clinico y para el ecografista ya que los criterios utilizados para el diagnostico de gestaciones extrauterinas no son exactos en razon a que los niveles de la fraccion Beta de la gonadotropina corionica humana (B-HCG
) se encuentran elevados debido a la gestacion intrauterina, por lo que su diagnostico requiere de un alto grado de sospecha por parte del ecografista.
Data from these 2 specimen types have been used to create a precision profile for both PAPP-A and hCG (insufficient data are available for evaluating the free b-hCG
subunit or the dimeric inhibin-A).
Initial treatment is based on symptoms, clinical findings and elevated b-HCG
The only adverse obstetric outcome associated with low free b-HCG
was in creased risk of fetal loss at or beyond 24 weeks' gestation (odds ratio 2.56).