BARF0BamHI (Bacillus amyloli) A Rightward Frame 0 (enzyme)
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References in periodicals archive ?
Spender et al., "Updated EpsteinBarr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV," The Journal of General Virology, vol.
Specifically, these authors indicate that all the latency type I genes such as Bam HI-A rightward reading frame (BARF0), EBERs, EBNA1, and LMP2A have a synergetic effect on these processes and contribute to the downregulation of the mature miR-200 family and the subsequent upregulation of the E-cadherin transcription repressors, zinc finger E-box binding factor 1 (ZEB1) and ZEB2, resulting in the inhibition of E-cadherin expression and induction of the epithelial-to-mesenchymal transition (EMT) [95].
It is classified as latency type I because the expressed latent genes are restricted to BARF0, EBERs, EBNA1, and LMP2A, excluding EBNA2 or LMP1 which are essential for its transforming ability [107-109].