) operates through two primary businesses, HD Vest, the No.
Among the target genes are BCL6interacting corepressor (Bcor
) and RuvB-like protein 1(Ruvbl1), two chromatin modifiers studied in various chromatin complexes [34-38].
 reported 2 primary renal sarcomas demonstrating BCOR-CCNB3 gene fusions with histologic overlap with CCSK and positive immunoreactivity for BCOR
, cyclin D1, TLE1, and SATB2 in the neoplastic cells.
More recently, a new subtype of Ewing-like sarcomas has been defined by the fusion of the BCOR
(BCL6 corepressor) and CCNB3 genes, which are nonadjacent genes on the X chromosome.
The genes sequenced were part of a custom, targeted next-generation sequencing amplicon panel testing for 68 hematologic malignancy-associated genes (ABL1, ASXL1, ATM, BCOR
, BCORL1, BIRC3, BRAF CALR, CBL, CDKN2A, CEBPA, CSF1R, CSF3R, DDX3X, DNMT3A, ETV6, EZH2, FAM5C, FBXW7, FLT3, GATA2, GNAS, HNRNPK, IDH1, IDH2, IL7R, JAK2, KIT, KLHL6, KRAS, MAP2K1, MAPK1, MIR142, MPL, MYC, MYCN, MYD88, NF1, NOTCH1, NOTCH2, NPM1, NRAS, PDGFRA, PHF6, POT1, PRPF40B, PTEN, PTPN11, RAD21, RIT1, RUNX1, SETBP1, SF1, SF3A1, SF3B1, SMC1A, SRSF2, STAG2, TBL1XR1, TET2, TP53, TPMT, U2AF1, U2AF2, WT1, XPO1, ZMYM3, and ZRSR2) (TruSeq Custom Amplicon, Illumina Inc.) based on previously described analyses [12,13].
(1) The phenotype features of OFCD and Lenz microphthalmia syndrome overlap in many points, and these 2 syndromes are likely to result from defects in alternative functions of BCOR
. Lenz microphthalmia syndrome is inherited in an X-linked recessive pattern, by a mutation in the BCL (6) interacting corepressor gene, BCOR
) said it has closed its private offering of 4.25% convertible senior notes due 2019.
Blucora Inc (BCOR
) shares climbed 20.18 percent to $17.91 in after-hours trading.
serves the fitness industry by leveraging Web and mobile technology.
Lytherm, Manniglas, Manniweb, Affinity, ZeroClearance, dBLyte, Lydair, Actipure, AcuPore, AMS, CRS Wrap, Cytherm, BCor
, LyPore, BioPak
Terrance Jalbert, University of Hawaii at Hilo Jonathan Stewart, Abilene Christian University Karl-Johan Moritz, University of Hawaii at Hilo Table 1: Sample Firms Company Ticker Data Start Data End Astrazeneca AZN 4-6-1999 2-6-2004 Autoliv ALV 1-2-1998 2-6-2004 Biacore BCOR
1-31-2000 2-6-2004 Electrolux ELUX 1-2-1998 2-6-2004 Ericsson ERICY 1-2-1998 2-6-2004 Maxim MAXM 1-2-1998 2-6-2004 Oxigene OXGN 1-2-1998 2-6-2004 Tele2 TLTOA 1-2-2000 2-6-2004 SW Match SWMAY 1-2-2000 2-6-2004 Company Observ Avg.
Tickers featured: ABI, AMGN, AMLN, BCOR
, BGEN, CELG, CEPH, CHIR, DNA, EXEL, GENZ, GILD, HGSI, IDPH, MDCO, MEDI, MICU, MLNM, NBIX, PFE, SQNM, TECH.