BCVABest Corrected Visual Acuity
BCVABest-Corrected Distance Visual Acuity (cataract surgery)
BCVABritish Cattle Veterinary Association (Gloucestershire, UK)
BCVABritish Columbia Volleyball Association (Burnaby, British Columbia, Canada)
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The third cohort included 6 subjects with BCVA of 20/200 or less, who received a single sub-retinal implantation of OpRegen.
This activity was maintained with an average improvement in BCVA of 6.5 letters at Day 90 following a single injection of THR-149.
Wilcoxon signed ranked test was used to assess statistical significance of pre and post-operative BCVA. P<0.05 was considered statistically significant.
Sample size was 73, keeping 95% improvement in BCVA in post-PPV patients7, at 95% confidence interval and 5% margin of error using WHO sample size calculations.
Gris and his colleagues reported that there was 23.6% increase in the number of patients having BCVA of 6/9 or better postoperatively11.
The change from pre-treatment to 1-year BCVA was significantly greater in group 1 than in group 2 (Table 1).
Mean BCVA improved from 0.71 +/- 0.19 logMAR and 0.75 +/- 0.11 logMAR before surgery to 0.450 +/- 0.21 logMAR and 0.41 +/- 0.18 logMAR at 6 months after DSEK and DMEK, respectively (Table 2; Fig.
Participants underwent monthly ophthalmic examination for: (a) intraocular pressure (IOP) monitoring via Goldmann Applanation Tonometry, (b) adverse event monitoring, (c) standardised BCVA assessment in ETDRS letters and (d) colour fundus photography.
The mean values of BCVA in both eyes were significantly lower in the PDR group (mean value of 0.45) in comparison with the values in patients with NPDR (mean value of 0.84) and WDR group (mean value of 0.83) (Graph 3).
Patients with bilateral impairment had a mean BCVA of 0.9 logMAR (range 0-2.30), whereas patients with unilateral disease had a mean BCVA of 1.02 logMAR (p = 0.54).