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BH3Bcl-2 Homology 3
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La regulacion positiva Mcl-1 mantiene la resistencia a la apoptosis en celulas infectadas pero en la degradacion de las proteinas, BH3 es la razon de la resistencia a la apoptosis (21,23).
Similarly, other values of angular velocities occurred twice in the regression model (for VRmax and VRcont): VcontSRot (velocity at the moment of contact in shoulder girdle rotation towards the playing side) was found in BH1, VmaxLHAA (Vmax during left hip abduction) in BH2 and VminLHAA (Vmin during left hip adduction) in BH3 (Table 5).
The hydrophobic cleft is also known as the receptor domain where the BH3 proteins bind and inhibit apoptosis (Figure 1) [9].
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains.
The BH3 domain of BAD is an amphipatic [sigma]-helix, which binds to Bcl-2 and Bcl-xL and neutralizes the apoptotic activity of BAD [88].
Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.
One family of such drugs, termed 'BH3 mimetics,' has recently advanced through clinical trials, in which the drugs showed remarkable activity in patients with certain leukemias and lymphomas.
Una de las proteasas secretadas es el factor de actividad proteasomal (CPAF), que degrada las proteinas proapoptoticas del dominio unico BH3, de la familia de proteinas Bcl-2.
Apesar disso, o seu controle por membros de outras familias, como por exemplo a BH3, ainda e insuficientemente determinado (12).
The activation mechanism of apoptosis is controlled by the anti-apoptotic proteins (Bcl-2, Bcl-xl) which bind to the BH3 domains of Bax and Bak, separate them and prevent their oligomerization [6].
Characteristic of compression and shear wave velocity have been obtained by down-hole seismic test in BH3 are shown in table(1-6) and Fig(1-22).
The development is a joint-venture between developers BH3, led by principals: Gregory Freedman, Charles Phelan and Daniel Lebensohn; alongside Gary Cohen, the developer of Island Estates, a 21-mansion community revered as one of “Aventura's Founding Families.”