BMCLSBishop Maher Catholic Leadership Scholarship
BMCLSBiomedical and Clinical Laboratory Sciences (University of Edinburgh; UK)
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References in periodicals archive ?
Thus, using the central estimate of the BMD or BMC (maximum likelihood estimate) instead of the lower statistical confidence limit (BMDL or BMCL) as the point of departure would result in a 1-to 3-fold difference in the estimated risk levels (Figures 2 and 3).
The BMDL values were up to 4.6 times higher than the empirical NOAELs (range, 0.5-4.6), and the BMCL values were up to 3.9 times higher than the empirical NOAELs (range, 0.2-3.9) (Tables 1 and 3).
Using the BMDL or BMCL as the point of departure in the risk assessment of noncarcinogenic compounds rather than the BMD or BMC central estimate is generally characterized as a conservative assumption (in the health-protective sense).