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BRDT is involved in the chromatin remodeling process during the generation of sperm in the testis.
JQ1 subverts that process by binding to a pocket of BRDT that is necessary for the chromatin remodeling to take place.
"Small-Molecule Inhibition of BRDT for Male Contraception." Cell 150: 673-684, 17 August 2012.
Determination of expression level of BRDT in normal and cacerby real-time quantitative RT-PCR.
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