Under a letter of agreement between WVU and BRNI
, WVU would integrate all of its neurosciences research under a new WVU Blanchette Rockefeller Neurosciences Institute with the aim of advancing knowledge through team-based research.
Shana Phares, CEO at BRNI
adds, "We are so proud of Helen and the work she has led at BRNI
There are, of course, some exciting new directions in developing drugs to treat AD, including those being pursued at BRNI
(see this issue).
These data from BRNI, together with the collective clinical experience with AD, the characteristic pathologic changes, the genetic mutation linked to familial AD, and curative effects of non-toxic PKC [epsilon] activators leads us to a new synthesis for both the early causes and the consequent pathologic changes of the disease.
An exhaustive drug screening program is now ongoing at BRNI to develop and test optimal drugs that activate PKC [epsilon]--without causing toxicity.
Other evaluation/diagnosis strategies are under development, including a skin biopsy technique now being studied at BRNI.
PCPs will use this more than any other group of practitioners and BRNI will be providing extensive education prior to the registry being fully implemented.
The first-ever West Virginia Alzheimer's Disease Registry to collect data on patients and the disease in order to better inform state allocation of resources and to help guide BRNI