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The BSL-3 laboratory is one of the largest in Pakistan, with experienced staff that have been well-trained in Tuberculosis (TB) diagnostics and bio-safety practices.
"The leadership of QU-BRC is working so hard to establish BSL-3 in the country because it will open a lot of doors in terms of research.
Traditionally, the air within a BSL-3 laboratory is changed eight to 12 times per hour, but it isn't uncommon to find the heat load from the equipment within drives the air exchange rate higher.
BSL-4 builds upon the containment requirements of BSL-3 and is the highest level of biological safety.
BSL-4 laboratory orientation training assumes that the person has already mastered all procedures for safe and secure handling of infectious agents at the BSL-2 and ideally BSL-3 levels.
A major proliferation of high-containment BSL-3 and BSL-4 labs is taking place in the United States, according to the literature, federal agency officials, and experts.
Maybe Washington, DC, the city has no facilities (I don't know that they don't nor do I know what the universities have), but I can assure you that the Washington, DC, area has fully operational containment facilities operating at BSL-3.
BSL-3 facilities must be isolated from other areas having open access.
The high case-fatality ratio of HCPS (40%), coupled with its airborne transmission by captive rodents, has led to classification of the agents of HCPS as biosafety level 3 (BSL-3) in tissue culture and BSL-4 in reservoir host rodents.
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