) are a class of psychotropic drugs that function as positive allosteric modulators on the gamma-aminobutyric acid-A (GABAA) receptors in the brain.
These disorders can be treated with a range of psychiatric drugs, including a group of substances called benzodiazepines (BZDs
Serotonina Fluoxetina 1 Atidepressivos triciclicos Amitriptilina 1 BZDs
longa acao Diazepam 3 Bromazepam 8 BZDs
curta--media acao Alprazolam 2
) are central nervous system (CNS) depressants which are widely used to treat insomnia and anxiety, despite having long-term adverse side effects.
Medical disease, gait or balance impairment, cognitive impairment, medication use, and falling history might increase the risk of falls. Among medications and diagnoses, alpha-blockers, nonbenzodiazepine (non-BZD) sleep aids, BZDs
, H2-blockers, lithium, antipsychotics, atypical antidepressants, anticonvulsants or mood stabilizers, laxatives or stool softeners, and a diagnosis of dementia or Alzheimer's disease increase the risk of falling in psychiatric inpatients.
) act as positive allosteric modulators on gamma amino butyric acid (GABA) type A receptors .
) are widely used as anxiolytics, sedative hypnotics, anticonvulsants, and muscle relaxants or for anesthesia induction.
It has been used in the extraction, isolation, and clean-up of several compounds present in complex matrices, as in the analysis of veterinary drugs, such as anthelmintics [17-19], benzimidazoles (BZDs
) , nitroimidazoles , sulfonamides (SAs) [22, 23], quinolones (QNs) , tetracyclines (TCs) , nonsteroidal anti-inflammatory drugs (NSAIDs) [26, 27], and [beta]2-agonists [28,29] present in animal tissues, foodstuffs, lacteous products, and water.
) were commonly prescribed medications in the treatment of anxiety disorders in the last few decades of [20.sup.th] century.
Sedative-hypnotic agents include several barbiturates, benzodiazepines (BZDs
), non-BZD benzodiazepine-receptor agonists (BzRAs), a melatonin-receptor agonist (ie, ramelteon), and an orexin-receptor antagonist (ie, suvorexant).
Todas las BZDs
tienen las mismas acciones farmacologicas, son ansioliticas a dosis bajas e hipnoticas a dosis elevadas, con un inicio de accion rapido, tambien tienen efecto anticonvulsivante y relajante muscular; las diferencias fundamentales entre ellas son de tipo farmacocinetico.
In the 1960s, the, toxic liability of sleeping pills was drastically reduced when benzodiazepines (BZDs
) were introduced.