Luke, "Effect of urinary pH and diatrizoate on Bence Jones protein
nephrotoxicity in the rat," Kidney International, vol.
0 g/L) IgG[Kappa] peak and a small Bence Jones protein
peak (16 mg/d) migrating in the same regions as originally noted.
No M protein, Bence Jones protein
, accumulation of gallium, or abnormal cells in bone marrow were detected, which suggested that the plasmacytoma had not developed into multiple myeloma.
A systemic workup for multiple myeloma included a bone marrow biopsy, bone scan, quantitative immunoglobulin assay, and measurements of hematocrit, white blood cells, blood urea, serum creatinine, serum electrolytes, serum calcium, and Bence Jones proteins
These investigations included a complete blood cell count, measurement of serum calcium and creatinine levels, serum protein electrophoresis and immunoelectrophoresis, urinalysis for Bence Jones protein
, evaluation of [[beta].
Findings on bone marrow biopsy were normal, as were the results of immunologic laboratory analysis, including an assay of Bence Jones proteins
Our objectives, in a prospective study with consecutive samples received for SPEP, were to evaluate (a) whether the addition of serum FLCs identified extra patients with monoclonal gammopathies at the time of a first request for SPEP; (b) whether serum FLCs could replace urinalysis for Bence Jones protein
(BJP); and (c) the cost and quality implications of routinely measuring serum FLCs.
The first laboratory test for a protein cancer marker, the Bence Jones protein
in urine, was described in 1847.
Tests for Bence Jones protein
in the urine and for serum myeloma protein were negative.