Bone to total alkaline phosphatase ratios improve sensitivity and specificity of bone alkaline phosphatase
The levels of bone Gla-protein (BGP or osteocalcin) and bone alkaline phosphatase
(B-ALP) reflect the changes of bone formation most sensitively and specifically while that of C-terminal telopeptide of type I collagen (CTX) indicates the changes of bone resorption most satisfactorily.
6% increase in lumbar spine volumetric bone mineral density at the end of the study and an average 16% increase in bone alkaline phosphatase
in comparison with the placebo group at each time point measured.
The phytase dose-dependent (linear and quadratic) increase in plasma P and decrease in plasma calcium, alkaline phosphatase activity and bone alkaline phosphatase
activity, indicates that phytase facilitated digestion of dietary phytatephosphorus, preventing excessive bone resorption or demineralization.
The study participants' tested levels of increased bone alkaline phosphatase
were significant at p [is less than] .
The reduction in bone alkaline phosphatase
supports this suggestion.
During a 24-month treatment and followup period, levels of N-terminal telopeptide of type I collagen (NTx) and bone alkaline phosphatase
Bone alkaline phosphatase
activity and serum N-telopeptide concentration increased appreciably over the same period of time.
Their bone alkaline phosphatase
level, a marker of bone synthesis, had climbed from 7.
Different responses of bone alkaline phosphatase
isoforms during recombinant insulin-like growth factor-I (IGF-I) and during growth hormone therapy in adults with growth hormone deficiency.