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References in periodicals archive ?
She is co-founder and chair of the Breast International Group that includes more than 56 cooperative groups, more than 10,000 experts, and links more than 3,000 hospitals.
Research published in the Journal of Clinical Oncology in April, from the Breast International Group, a collaboration of global researchers into breast cancer, found women on statins lived longer than those who did not take them Over eight years of follow-up on almost 8,000 women, during which time 1,432 patients saw their cancer come back, the disease-free survival rate was 18% higher in the women already on statins at the start of the study, compared with those who were not.
The Breast International Group B1G 1-98 trial randomized 6 193 postmenopausal women to a double blind trial of tamoxifen, letrozole alone or in sequence and studied the impact of treatment adherence on Disease Free Survival (DFS).
The Breast International Group (BIG) 1-98 Trial included 4,922 breast cancer patients; one group was allocated to tamoxifen and the other to letrozole (an aromatase inhibitor).
Moreover, the decreased estrogen levels play a key role in inhibiting the growth of breast tumors.[sup][4] However, the Breast International Group 1-98 study shows that AIs therapy can also be accompanied by adverse events, such as thromboembolic events, cardiac events, and cerebrovascular accidentsaccounting for nearly 1%.[sup][1] At present, whether AIs treatment can increase risk of cerebrovascular or cardiovascular accidents in patients with breast cancer is not clear in the literature.
M2 EQUITYBITES-December 3, 2015-The International Breast Cancer Study Group and the Breast International Group selects Biovica's DiviTum technology
The CYP2D6 genotype was reviewed in 4393 women from the Breast International Group (BIG 1-98) trial, and no significant difference in the risk of breast cancer recurrence was found.
The HERA trial is being conducted by the Breast International Group (BIG) with funding from Roche.
Recently, two large randomized trials--ATAC (Arimidex, Tamoxifen, Alone or in Combination) and BIG (Breast International Group 1-98)--failed to identify any significant difference in clinical outcome among EM, IM, and PM patients treated with tamoxifen (J.
IMPAKT has been launched by the Breast International Group (BIG) and the European Society for Medical Oncology (ESMO), in collaboration with the St Gallen Primary Therapy of Early Breast Cancer Conference and the three European Breast Cancer Conference (EBCC) partners [The European Organisation for Research and Treatment of Cancer (EORTC) Breast Cancer Group, The European Society of Breast Cancer Specialists, and Europa Donna--The European Breast Cancer Coalition].
The networks are The Breast Cancer Intergroup of North America (TBCI), based in the United States, and the Breast International Group (BIG) in Brussels, Belgium.