Evaluation of a fully automated assay to measure C-telopeptide
of type I collagen in serum.
Early changes in serum N-telopeptide and C-telopeptide
cross-linked collagen type I predict long-term response to alendronate therapy in elderly women.
Increases in C-telopeptides
serum levels were associated with a significantly greater risk for the development of a new morphometric vertebral fracture (p < 0.
Measurement of bone degradation products in serum using antibodies reactive with an isomerized form of an 8 amino acid sequence of the C-telopeptide of type I collagen.
Serum C-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) Free y-carboxy glutamic acid TRAP Urine Calcium Hydroxyproline (total, free) Pyr (free, total) Dpd (free, total) NTx C-telopeptide (ICTP) Hydroxylysine glycosides Table 2.
The peptide-linked forms are mixtures generated from N- and C-telopeptides of collagen.
Recently, immunoassays for the measurement of urinary free Dpd , cross-linked N-telopeptides of type I collagen (NTx) , and linear C-telopeptides of type I collagen (CTx)  were developed.
A new assay (Serum CrossLaps [TM] One Step ELISA) for the determination of serum concentrations of the C-telopeptide
of type I collagen ([beta]-CTx) has been developed recently (6) and applied clinically (7); therefore, we found it interesting to determine whether it can detect the inhibition of osteoclast activity that follows oral calcium loading.