2, named Caga
, regional director of PIA's office in Caraga, as OIC of the PIA central office.
The vital components of cagPAI, cagA
and cagE, were also found in the cagPAI positive samples (data not shown).
The serum IgG levels against CagA
were also assessed using the commercial ELISA kit (Diagnostic Bi-oprobes, Milano, Italy).
pylori discharges multiple effector proteins/toxins, such as cagA
and vacA, leading to host tissue damage.
pylori isolate, and the same technique was employed to establish presence or absence of cagE, cagA
, iceAl, iceA2 babA2, and babB genes.
The Role of CagA
in the Gastric Biology of Helicobacter pylori.
pylori CagA+ strains has been reported, but as CagA
is capable of triggering strong host inflammatory response, there is a possibility of induction of atherosclerosis and coronary heart disease due to such chronic inflammatory state.
pylori strain, such as babA2, cagA
, vacA, and iceA1 have been identified and involved in pathogenesis of infection.
Based on the presence or absence of cagA
, a gene encoding the CagA
protein, in its bacterial genome, H.
pylori immunoglobulin G (IgG) and CagA
IgG antibodies in asymptomatic blood donors.
However, while some immune responses to certain antigens persist for decades (especially CagA
), antibody titres against other antigens decrease within a shorter period, also depending on the Ig-class tested .
and vacA genes in saliva and dental plaque [31-33], but its frequency has not been extensively studied in Mexico.