CAPRIE


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AcronymDefinition
CAPRIEClopidogrel vs Aspirin in Patients at Risk of Ischemic Events
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References in periodicals archive ?
The incidence of thrombocytopenia and neutropenia induced by clopidogrel was reported to be 0.26 and 0.10%, respectively in CAPRIE study (3).
Clopidogrel, another antiplatelet drug that acts differently from aspirin, was shown to be beneficial in the Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) study (Lancet 1996;348:1329-39).
Data from the late 1990s demonstrated the efficacy and safety of combined therapy with aspirin and a thienopyridine derivative for reducing stent subacute thrombosis rates from 2% to as low as 0.5% (Moussa and others 1999; Bage and others 1998; Leon and others 1998; CAPRIE 1996).
He cited the findings of the Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) trial, in which the reduction of stroke, recurrent MI, and vascular death was 9% greater with clopidogrel than with aspirin in patients with recent ischemic stroke, recent MI, or PAD (Lancet 1996;348:1329-39).
CAPRIE trial demonstrated that clopidogrel is more effective than aspirin in reducing event rate and the rate of rehospitalisation in patients with recent ischemic stroke, myocardial infarction or symptomatic peripheral arterial disease.
A randomized, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE): CAPRIE Steering Committee.
Gunluk 75 mg klopidogrel kullanimi ile 325 mg aspirin tedavisinin karsilastirildigi CAPRIE calismasinda, klopidogrelin guvenilirlik ve katlanabilirlik profilinin aspirin ile benzer oldugu saptanmis ve notropeni ve trombositopeni acisindan aralarinda bir fark saptanmamistir (13).