CCR8 - What does CCR8 stand for? The Free Dictionary
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|CCR8||C-C Chemokine Receptor 8 (gene)|
References in periodicals archive
61) Notably, malignant melanoma cells often express high levels of CCR8
and use CCL1-CCR8
to enter into the lymph node parenchyma, forming lymph node metastases.
This translocation creates NPM-ALK (Nucleophosphmin anaplastic lymphoma kinase) gene with transforming potential,7 while other mutations are also implicated like defective expression of TCR, CCR8
, and CCR10.
Typically, CXCR3 and CCR5 are preferentially expressed on polarized Th1 cells, whereas CCR3, CCR4 and CCR8
have been associated with the Th2 phenotype.
In addition, more mRNA for CCR8
could be detected after application of Ni[SO.