CCTGACongenitally Corrected Transposition of the Great Arteries
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We present a case of incidental detection of isolated CCTGA in a patient in his fourth decade of life, who presented with dizziness, seizures, and loss of consciousness.
2D echocardiography established the presence of congenitally corrected transposition of great arteries (CCTGA) (Figure 1(b)).
CCTGA with third-degree AV block, right ventricular hypertrophy, and low heart rate indicated implantation of permanent pacemaker into the patient.
Isolated CCTGA occur without any associated anomalies but can also be accompanied with complications.
In about 20 to 50% of CCTGA patients, TR occurs in varying degrees ensuing substantial morbidity and mortality.
had reported a case of CCTGA that was diagnosed on presentation of patient with acute myocardial infarction.
In CCTGA retrospective multi-institutional studies clearly demonstrate an increasing incidence of systemic and ventricular dysfunction and clinical congestive heart failure with advancing age [24, 25].
(i) Primary heart transplantation (newborn HTx for HLHS or Ebstein's anomaly) (ii) Eisenmenger syndrome with simple CHD with left to right shunting (acyanotic) (iii) Tetralogy of Fallot (repaired or palliated), and other complex CHD (cyanotic) (iv) Univentricular heart with and without Fontan circulation (v) Systemic right ventricle (CCTGA or TGA after atrial switch operation) HTx: heart transplantation; HLHS: hypoplastic left heart syndrome; CHD: congenital heart disease; CCTGA: congenitally corrected transposition of the great arteries; TGA: transposition of the great arteries.
The overall prevalence of renal dysfunction--defined as a calculated creatinine clearance rate of less than 60 mL / min--was 36%, with prevalence rates of 56% in patients who had a Fontan procedure, 37% in those who had CCTGA, and 18% in patients following DTGA.