CCVR is an effective contraceptive as illustrated by its low Pearl index.
In the study conducted by Tuppurainen et al (2004), (22) it was found that the total HDL and LDL cholesterol level remained unchanged while triglyceride level increased from baseline from CCVR use.
The effect of CCVR on liver function was not clinically relevant with mean percentage change from baseline value being total bilirubin -0.23%, SGPT-0.18% and SGOT-0.35%.
In our study, CCVR was not associated with an increased risk of cervical or vaginal abnormalities.
CONCLUSION: From the present study, it can be concluded that CCVR is an effective contraceptive with good cycle control, minimal systemic or local adverse effects along with low incidence of spontaneous expulsion and higher level of user and partner acceptability and probably with a high contraceptive efficacy rate.
The combined contraceptive ring Ccvr (nuvaring) and spermicide comedication.
The combined contraceptive vaginal ring (Ccvr (nuvaring)) and lipid metabolism: a comparative study.
The combined contraceptive vaginal ring, Ccvr (nuvaring): an international study of user acceptability.
One of the advances in the contraceptive field has been the development of combined contraceptive vaginal rings (CCVRs).