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CD15Cluster of Differentiation 15
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The immunohistochemistry staining results showed these cells to be CD30+ (strong and diffuse); CD15 and PAX5 were positive in a few of these cells.
13] None of our cases stained for CEA or CD15 (LeuM1), and it has been recommended that these antibodies be used for separating mesothelioma from adenocarcinoma and other epithelial neoplasms, as CD15 and CEA generally lack reactivity with mesothelioma cells.
Sonuc: Laboratuarimizda epiteloid malign mezotelyoma acisindan kalretinin, CK5/6, adenokarsinom acisindan CEA ve CD15 ve bunlara eklenen EMA ve TTF-1'den olusan bir panelin hemen tum olgularda sorunu cozdugunu gorduk.
Prognostic impact of CD15 expression and proliferative index in the outcome of children with classical Hodgkin lymphoma.
In our experience, a reasonable basic panel of antibodies to aid in the diagnosis of most common childhood neoplasm should include pancytokeratin (cytokeratin AE1-AE3), epithelial membrane antigen, vimentin, synaptophysin, CD99, terminal deoxynucleotidyl transferase, CD43, myogenin, CD1a, placental alkaline phosphatase, [alpha]-fetoprotein, CD30, CD15, CD20, and CD3, although the use and interpretation of IHC should always be performed within the context of the lesion histomorphology, pattern of expression and intensity of the IHC stain, and proper evaluation of positive and negative controls.
Immunohistochemical stains revealed the large cells to be positive for CD30 and CD15 (Figure 3) and negative for Oct2 and Bob.
Two of these were diagnosed as nodular lymphocyte predominant HL (CD45 and CD20 positive, CD15 and CD30 negative) and were excluded.
Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor.
The following IHC stains were performed: CD45RB, CD3, CD20, CD15, CD30, CD43, CD45RO, BZLF-1, and EBER-1.
Immunohistochemistry demonstrated positivity for leukocyte-common antigen (LCA), CD20, and CD45RO without atypical lymphocytes, and negativity for CD15 and CD30.
68) Renal cell carcinoma marker and CD15 can also be useful, but the sensitivity and specificity of these markers for renal cell carcinomas is significantly lower than those of PAX8 or PAX2.
Flow cytometric analysis showed that these blasts were positive for myeloperoxidase, CD15, CD33, CD13, CD14, and CD4.