CDC7Cell Division Cycle 7
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Under this worldwide exclusive licensing agreement with Columbia University and Memorial Sloan Kettering Cancer Center, Lin BioScience plans to develop this potent CDC7 inhibitor (LBS-007) against a wide range of cancers.
CDC7 is one of two heterodimeric kinases involved in the cell cycle regulation of eukaryotic DNA replication.
Activated at the G1/S phase transition, CDC7 activates the helicase that unwinds DNA in preparation for cellular DNA replication.
Funeral I [reissued in 1995AP]; Funeral II (z58c+860) -- Virgin Veritas 5 45159-2 (formerly EMI CDC7 49635-2) with odes z323, 339