CDGEConstant Denaturant Gel Electrophoresis
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For example, DGGE and CDGE are sensitive to single-base changes but require a GC clamp for robust melting profiles and have decreased sensitivity in GC-rich regions (DGGE) (27) or regions containing multiple melting domains (CDGE) (28).
(*) Data are from Hayes et al.[3] CDGE indicates --; SSCP, single strand conformational polymorphism; PCR, polymerase chain reaction; ELISA enzyme-linked immunosorbent assay; EIA, enzyme immunoassay; RIA, radioimmunoassay; and IRMA, immunoradiometric assay.