CDNPCharles Darwin National Park (Australia)
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Based on a clinical neurological diagnostic examination performed by trained physical therapists, the population could be divided into three groups: T2DM without cdNP (D-; n = 28), T2DM with cdNP (D+; n = 82), and nondiabetic healthy controls without cdNP (C; n = 35).
Patients with T2DM were classified as having peripheral cdNP based on at least one of two positive criteria: a VPT exceeding the normality cut-off of 95% or a DNS score of [greater than or equal to] 1/4.
The present study was conducted to investigate respiratory muscle strength and function in T2DM and its relation to NP by comparing [PI.sub.max], [PE.sub.max], and PEF between T2DM patients with cdNP, T2DM patients without cdNP, and healthy controls.
However, an accumulating effect of cdNP and T2DM could not be ascertained.
They provided the first data regarding cdNP and concluded that cdNP was associated with substantially impaired respiratory neuromuscular function in patients with T2DM, when stimulating the nonvolitional phrenic nerve.
Our findings regarding both strength impairment (CST, p = 0.013) and total balance changes (p = 0.025) with its subtest "tandem stance" (p = 0.022) endorse the earlier research results in T2DM and cdNP on gait [53].