CDR3Complementary-Determining Region 3 (aka Third Complementarity-Determining Region; molecular genetics)
CDR3Chain Determining Region 3 (genetics)
References in periodicals archive ?
Puisieux et al., "T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor beta-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases," Research in Immunology, vol.
Chronic lymphocytic leukemias utilizing the Vm-21 gene display highly restricted V2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.
One group from Japan identified clonally expanded TCR beta CDR3 amino acid motifs of some PLP-specific T cells which were homologous to those of T cells within the MS lesions, showing that the PLP-specific T cells can infiltrate MS lesions [110].
Here he claimed that though the previous regime, bowing to public pressure, had in its latter stages finally begun to exhibit works of the French school in the Grande Galerie and in the Galeries du Bord de l'Eau, 'aucune intelligence n'avait preside au choix des toiles exposees, aucun ordre n'y avait ete apporte, aucun catalogue n'en avait ete dresse qui put renseigner le visiteur et l'artiste a travers cette confusion' (CdR3, p.
The sequence of complementarity-determining region 3 (CDR3) of the H chain was utilized for further classification.
The company received two new oil rigs in 2016, Doyon 142 and Nabors CDR3. It also announced it had contracted with Doyon Drilling to build a powerful, extended-reach drilling rig with the ability to drill to thirty-three thousand feet.
The CDR3 domain in the V region of both [kappa] and [lambda] FLCs interacts with THP; the binding affinities of FLCs for THP are related to the amino acid composition of the CDR3 domain [29].
(16) The antibodies exhibited extensive somatic mutation and the CDR3 segments of the H chain variable regions were unusually long.
Clonotypic B lymphocytes have been identified in patients with MM and are monoclonal and share identical, rearranged CDR3 sequences with the patient's myeloma cells.