CIBPCentre International Blaise Pascal (French library)
CIBPCast Iron Bridge Plug (oil industry)
CIBPCancer-Induced Bone Pain
CIBPCalcium- and Integrin-Binding Protein (thrombosis research)
CIBPComputer Integrated Building Processes (building industry; National Institute of Standards and Technology)
CIBPContinuous Infraclavicular Brachial Plexus (pain medicine)
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References in periodicals archive ?
However, after calpain inhibition, the TRAP-positive cell count was significantly decreased in the sarcoma + inhibitor group comparing with the sarcoma + vehicle group ( P < 0.05) [Figure 3]b, indicating that the osteoclastogenesis process could be blocked with calpain inhibitor in vivo in the CIBP rats.{Figure 3}
On POD 14, CIBP rats of all groups were subjected to the radiology assessment.
This study shows that the calpain inhibitor can alleviate mechanical hyperalgesia of bilateral hind paws determined by MWT testing in CIBP rats in vivo .
[sup][20],[21] Until date, there has not been any study that reported focusing on the CIBP model and osteoclastogenesis, therefore, we had very few references to consult.
Therefore, bilateral hyperalgesia, or "mirror-image pain," was revealed in CIBP rats.
Interestingly, our study demonstrates that a calpain inhibitor can also ameliorate mirror-image pain through increase of MWT of the nonsurgical side hind paws in CIBP rats, suggesting that calpain might somehow be involved in the neuropathic pain mechanism.
The study design data were extracted and classified using a predefined data extraction form that designated the animal used (sex, species, and strain), the CIBP model type (type of cancer cell and site of tumor injection), the intervention type, and the outcome measures (pain-related behavior, macroscopic features, and histological, and biochemical measurements).
Finally, we selected eight animal model studies of CIBP for analysis.
We analyzed the animal models for CIBP in eight studies (Table 1).
CIBP is a common symptom in cancer patients, and background pain, spontaneous pain, and movement-induced pain are the 3 main characteristics of CIBP.
CIBP has a complicated relationship with pathological processes, neuroimmune mediators, tumor growth, and neuropathic conditions [24].
Our results revealed that injection of Walker 256 mammary carcinoma cells into the cavity of the tibia was the most frequently used CIBP animal model [15-19].