CIN2Cervical Intraepithelial Neoplasia Grade 2
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Among 5,258 females who received three placebo shots, 1 developed AIS, 15 developed CIN3, and 5 developed CIN2 during an average 17 month follow-up, Dr.
LGSIL, which denotes low-grade squamous intraepithelial lesion, equates to ccllular changes associated with mild dyplasia, cerpical intraepithelial neoplasia 1 (CIN 1) or human papillomapirus (HPV); HGSIL, high-grade squamous intruepitbelial IcaL2asion, equates to moderate dysplasia (CIN2) or severe dysplasia (CIN 3 or carcinoma in situ).
Among these women who had post coital bleeding, 70% had benign findings cell carcinoma and other with CIN2.
For these women, HPV testing detected significantly more CIN2 lesions than cytology (108 vs.
HPV DNA tests have excellent sensitivity (around 95%) for CIN2 or higher, but specificity is low (ranging in the 20s and 30s).
Test accuracy for detecting CIN2 or higher in patients with ASC-US.
The primary end point of the analysis was cervical intraepithelial neoplasia grade 2 (CIN2) or higher (as confirmed by histology) or cervical cancer found via the screening test.
The method with the highest specificity for detecting CIN2 as described in this article is__.
Why young women should be screened for cervical cancer: the distinction between CIN2 and CIN3.
In 6 cervical cases, there was a slight discordance in the grading of dysplasia for the low-grade category, between cervical intraepithelial neoplasia grade 1 (CIN1) and condyloma (cases 5-10); and in 2 cases, discordance concerned the high-grade lesions (CIN2 versus CIN3/carcinoma in situ; cases 3 and 4).
In a study of 24,661 women in Italy, the sensitivity and specificity of P16-INK4A to detect CIN2 or greater was 88% and 61 %, respectively.