CIP1


Also found in: Medical.
AcronymDefinition
CIP1CDK (Cyclin-Dependent Kinase)-Interacting Protein 1
CIP1COP1-Interactive (Caspase-1 dominant-negative inhibitor pseudo-ICE) Protein 1
References in periodicals archive ?
In a multicultural neighbourhood, that can be incredibly difficult (CIP1, December 6, 2005).
(53) The same authors also found that IP6 was capable of inhibiting the G1 phase of the cell cycle, increasing its arrest in prostate cancer cells, as well as upregulating p27/Kip1 and p21/ Cip1 which contribute to this effect.
The data showed that endometrial malignant tumors possess high proliferative activity, overexpression of p53 and high expression of p21(WAF1/ CIP1).
That group had called the gene CIP1. Then a casual phone conversation between BoylorNs Stephen J.
Guo, "Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and downregulation of tumor suppressor p53 and p21WAF1/ CIP1," Breast Cancer Research and Treatment, vol.
(5-6) p53 induces the expression of several genes, such as the cyclin-dependent kinase inhibitor p21 (also called WAF1 or CIP1), which leads to growth arrest in G1.
Other genes that have emerged as significantly mutated genes in whole-exome sequencing studies of serous endometrial carcinomas are SPOP, a putative tumor suppressor gene; CDKN1A [cyclin-dependent kinase inhibitor 1A (p21, Cip1)], a bona fide cancer gene; TAF1; HCFC1R1 [host cell factor C1 regulator 1 (XPO1 dependent)]; CTDSPL [CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like]; YIPF3 (Yip1 domain family, member 3); and FAM132A (family with sequence similarity 132, member A) (17, 18).
the control of the 1998 cell cycle 9 CDKN 1A (p21, functions as a Roman-Gomez et Cip1) regulator of cell al.
Assoian, "Regulation of p21(cip1) expression by growth factors and the extracellular matrix reveals a role for transient ERK activity in G1 phase," Journal of Cell Biology, vol.
For example, miR-128 has 6 predicted gene targets [pyruvate dehydrogenase kinase, isozyme 1 (PDK1); pyruvate dehydrogenase kinase isozyme 2 (PDK2); MTOR; phosphodiesterase 3A, cGMP-inhibited (PDE3A); phosphodiesterase 3B, cGMP-inhibited (PDE3B); FOXO1], and miR-141 is predicted to target 5 genes [PTEN; PDK2; cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A); CDKN1B;PDE3B].
Extensive lists of GSK-3 substrates or GSK-3 binding proteins have been reported and include amyloid precursor protein, APC, ATP-citrate lyase, axin, axil, [beta]-catenin, c-jun, Jun B, Jun D, Ci155, C/EBP alpha, CRMP2, CRMP4, CREB, CTP, cyclin D1, dystrophin, eIF2B, glycogen synthase, glucocorticoid receptor, heat shock factor 1, hnRNP, K-casein, KRP, MAB 1B, MAP 2, MAP 2C, MITF, c-Myc, L-Myc, alpha NAC nascent polypeptide-associated complex, NCAM, NDRG1, NDRG2, neurofilament L, neurofilament M, neurofilament H, Notch 1C, p21 CIP1, p53, presenilin, pyruvate DH, PP1 G-subunit, protein phosphatase inhibitor 2, stathmin, synphilin-1, RSK1, and Tau (https://thebiogrid.org/ and http:// www.genecards.org/).