The presence of sepsis, SIRS and/or MOF is a major and well established risk factor for the development of CIPNM.
When initial assessment indicates abnormal neurological function an electromyogram is recommended to diagnose CIPNM.
addition to their role in monitoring and helping to prevent and treat systemic inflammation and organ failure, nurses have an important task in the prevention of CIPNM by tightly controlling blood glucose levels.
Although this test had good specificity (94%) its low sensitivity (44%) meant that lower glucose levels did not predict the absence of CIPNM.
In all three studies, no significant differences were found regarding particular drugs and the onset of CIPNM.
Research into the long-term outcome of CIPNM is difficult to undertake.
No specific treatment for CIPNM is available and the management of neuromuscular weakness is primarily supportive (Garnacho-Montero et al.
2004), it is likely that the incidence of CIPNM will increase in the future.
In clinical practice, the diagnosis of CIPNM could be improved by systematically assessing every ICU patient following long-term mechanical ventilation and the maintenance of tight control of blood glucose level seems to be promising to reduce the incidence CIPNM, long-term disability, and mortality.
The appropriateness of specific weaning and rehabilitation protocols for the patient with CIPNM requires further study.
Large scale studies with rigorous methodology are required to gather further evidence of the existence of CIPNM and its impact on the individual and on society.