- Chromogenic In Situ Hybridization (CISH
) (Technique) Competitor Revenue Share (in %) in the US: 2019 & 2025
Regarding HER2 status, results of CISH
Venn diagram analysis revealed that 6 upregulated genes (CISH
, ERLIN1, FCRL1, IL1A, RPS6KA2, and SOCS3) and 9 downregulated genes (ADORA3, ARRDC3, BCOR, ERN1, FRAT1, HBB, KLHDC8B, TIGD3, and ZNF217) were present in the responses of neutrophils to either iRBC or LPS stimulation (Figures 1(d) and 1(e)).
Caption: FIGURE 1: Photomicrographs: lesion with papillary appearance showing exophytic projections of epithelial proliferation with benign appearance (a), transition zone of malignant neoplasm in the right vocal fold (b), well-differentiated SCC (c), dotted brown nuclei showing positive CISH
result for high-risk HPV (16/18) in LP (d), and in SCC (e).
Given the central role in controlling signaling of cytokines, in particular IL-2 , CISH
was selected as a candidate gene of human disease.
For the In Situ Hybridization procedure, the slides were de-paraffinized and then treated by the standard methods of rehydration according to the details of processes for performing CISH
reaction and then the probe was applied according the instructions of the manufacturing company (Zyto Vision GmbH.
In order to confirm the amplification of the HER2 gene we performed a dual color chromogenic (CISH
) assay using the Kit CISH[TM] HER2 SPOT-Light[R], Zymed (Invitrogen, USA) in the TMA sections.
In addition, the proliferation index was very high (80%) and Epstein-Barr virus (EBV) was detected by CISH
Few studies have investigated the impact of CISH
polymorphisms on TB and found an association between the variants and the risk of TB.
"Things As Others." Paper presented at Congress of Historical Sciences (CISH
), UNSW, Sydney, 2005.
The expression of HER-2/neu can be analyzed using immunohistochemistry (IHC) or in situ hybridization (ISH) techniques, like fluorescent in situ hybridization (FISH) and more recently, chromogenic in situ hybridization (CISH
) on formalin fixed paraffin embedded tissue sections7.