CKD-EPIChronic Kidney Disease Epidemiology Collaboration
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Patients' renal functions were estimated with the CKD-EPI equation, which is widely used in clinics.
The 2009 CKD-EPI creatinine equation is more accurate in estimating GFR and prognosis than the 2006 MDRD (Modification of Diet in Renal Disease) Study equation, and provides lower estimates of prevalence of decreased eGFR.
Comparative performance of the CKD epidemiology collaboration (CKD-EPI) and the modification of diet in renal disease (MDRD) study equations for estimating GFR levels above 60 mL/min/1.73 m2.
Model 2 included all variables of model 1 plus smoking, diabetes mellitus, dyslipidemia, and hypertension as factors, and BMI, HDL-cholesterol, triglycerides, glomerular filtration rate by CKD-Epi, and high sensitivity C-reactive protein (hs-CRP) as continuous variables.
In addition, the eGFR with the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation allows for more detailed analysis of renal function and discriminates patients with mildly reduced GFR (60-89 mL/min/1.73[m.sup.2]).
Three CKD-EPI estimations were calculated: [CKD-EPI.sub.creatinine], [CKD-EPI.sub.cystatin C], and [CKD-EPI.sub.creatinine-cystatin C] (4).
Recently, however, the use of the CKD-EPI equation in predicting GFR has also been suggested (10).
The CKD-EPI equation was found to be more accurate than the MDRD equation for patients with an eGFR of more than 60 mL/min/1.73[m.sup.2] i.e.
Values of creatinine were transformed to eGFR using the MDRD and Lund-Malmo (L-M) and CKD-EPI formulae.
Stevens, "Estimating GFR using the CKD epidemiology collaboration (CKD-EPI) creatinine equation: More accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions," American Journal of Kidney Diseases, vol.