Patients' renal functions were estimated with the CKD-EPI
equation, which is widely used in clinics.
The 2009 CKD-EPI
creatinine equation is more accurate in estimating GFR and prognosis than the 2006 MDRD (Modification of Diet in Renal Disease) Study equation, and provides lower estimates of prevalence of decreased eGFR.
Comparative performance of the CKD epidemiology collaboration (CKD-EPI
) and the modification of diet in renal disease (MDRD) study equations for estimating GFR levels above 60 mL/min/1.73 m2.
Model 2 included all variables of model 1 plus smoking, diabetes mellitus, dyslipidemia, and hypertension as factors, and BMI, HDL-cholesterol, triglycerides, glomerular filtration rate by CKD-Epi
, and high sensitivity C-reactive protein (hs-CRP) as continuous variables.
In addition, the eGFR with the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI
) equation allows for more detailed analysis of renal function and discriminates patients with mildly reduced GFR (60-89 mL/min/1.73[m.sup.2]).
estimations were calculated: [CKD-EPI.sub.creatinine], [CKD-EPI.sub.cystatin C], and [CKD-EPI.sub.creatinine-cystatin C] (4).
Recently, however, the use of the CKD-EPI
equation in predicting GFR has also been suggested (10).
equation was found to be more accurate than the MDRD equation for patients with an eGFR of more than 60 mL/min/1.73[m.sup.2] i.e.
Obecnie najszerzej stosowane wzory to MDRD i CKD-EPI
Values of creatinine were transformed to eGFR using the MDRD and Lund-Malmo (L-M) and CKD-EPI
It is worth to note that both the MDRD and CKD-EPI
study were performed in a much younger population.
Stevens, "Estimating GFR using the CKD epidemiology collaboration (CKD-EPI
) creatinine equation: More accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions," American Journal of Kidney Diseases, vol.