The purpose of this study was to compare the patterns of increases and decreases in cTnI and CKMB
mass in a series of nine MI patients who experienced an in-hospital myocardial reinfarction (MI extension) within 4 days of the initial MI event.
Most importantly, in chest pain patients, cTnT is increased in 30% of all patients despite normal CKMB
Waste blood specimens collected from all 1719 patients were used for analysis of cTnI and CKMB
Some troponin and CKMB
mass assays showed significantly higher 99th percentile cutoffs for males than for females and for blacks than for Caucasians.
Plasma cardiac troponin was measured by eight different assays and CKMB
mass by seven different assays: Abbott AxSYM (cTnI, CKMB
), Bayer Centaur (cTnI, CKMB
), Beckman Access (second-generation cTnI, CKMB
), Dade-Behring Dimension RxL (second-generation cTnI, CKMB
), Diagnostic Products Corporation (DPC) Immulite 2000 (cTnI), Ortho-Clinical Diagnostics (OCD) Vitros ECi (cTnI, CKMB
), Roche (third-generation cTnT, CKMB
), Tosoh AIA (second-generation cTnI, CKMB
11-13] Hence, this study has been aimed to compare the sensitivity and specificity of GPBB with those of MB and CKMB
within 4 h after the onset of chest pain.
Cardiac enzymes were more raised in patients with left circumflex related acute inferior wall MI with a mean CPK of 663 (U/L) and CKMB
of 89 (U/L), whereas in patients with RCA related acute inferior wall MI, CPK was 482 (U/L) and CKMB
was 70 (U/L).
The primary endpoints of this study were; increase in post-op CKMB
levels, intensity and duration of inotropic support and mechanical ventilation time.
In the alternating upper- and lower-extremity ischemia and the control group (groups B and C), the CKMB
peak release appeared after cardiopulmonary pump (group A: 64 (ranged 38.
Blood samples confirmed a large myocardial infarction with troponin-T of 9649 ng/L and CKMB
of >600 [micro]g/L.
The company's assays include AFP, CEA, PSA, Insulin, CKMB
, Troponin I 2nd Gen, Myoglobin, B-2 Microglobulin, Cystatin C, ACTH, Homocysteine and PAP.
In addition to Troponin T, rise in CKMB
level were considered as diagnostic of acute myocardial infarction.