CLB2Clearfil Liner Bond 2 (dental self-etching primer)
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At least three functions have been attributed to RMRP: processing of mitochondrial RNA that functions as a primer for mitochondrial DNA replication in mitochondria, endonucleotic cleavage of precursor 5.8S rRNA and processing of CLB2 mRNA that normally disappears rapidly as cells complete mitosis [51].
The malachite green binder was cloned into the 5'-untranslated region of CLB2 gene, which codes for a cell cycle protein that directs transition from G2 to mitosis.