Zadnik, "A summary of the findings from the collaborative longitudinal evaluation of keratoconus (CLEK) study.
Zadnik, "Collaborative longitudinal evaluation of keratoconus (CLEK) study: methods and findings to date," Contact Lens & Anterior Eye, vol.
Edrington et al., "Baseline findings in the collaborative longitudinal evaluation of keratoconus (CLEK) study," Investigative Ophthalmology & Visual Science, vol.
study established that age is a major factor in severity of KC.
Los lentes de contacto se utilizan en 90% de los casos de queratocono, ya sean blandos o rigidos y permeables a los gases; segun el CLEK (13) estos ultimos se emplean en 65% de los casos y con ellos se logra en 95% de los pacientes una agudeza visual de 20/40 o mejor.
Segun el CLEK, 12.3% de los queratoconos terminan en QPP (4).
Factors associated with corneal scarring in the collaborative longitudinal evaluation of keratoconus (CLEK) study.
According to the CLEK criteria, 39 eyes (10%) had mild keratoconus, 252 eyes (64.4%) had moderate, and 100 eyes (25.6%) had severe keratoconus.
Conflicting results among studies might be due to inadequate number of eyes within the different stages of keratoconus, differences in exclusion criteria (current or previous contact lens wear), measurement devices (slit scanning or laser scanning confocal microscopy), techniques for image acquisition and cell density calculation (image size, image location, automated or manual cell counting), and classification of disease severity (Krumleich-Amsler, CLEK, etc).
Therefore, we included a large number of keratoconic eyes (391 eyes) and classified eyes according to disease stage based on the CLEK recommendation and according to TCT.
(20.) Gordon MO, Steger-May K, Szczotka-Flynn L, et al; Clek
Collabonarive Longitudinal Evaluation of Keratoconus (CLEK
) Study Group.