ClFr and EtFr were further fractionated for the isolation of compounds (C1-C6) and (F1-F3), respectively (details of isolation and structural elucidation of these compounds will be published separately).
An HPLC method was developed for the analysis of the active ClFr and EtFr.
An HPLC method was developed to analyse the active terpene (ClFr) and flavonoid (EtFr) containing fractions.
The ClFr and Etfr of C droserifolia aqueous extract were found to have significant insulin-like effects in peripheral tissues, namely the stimulation of basal glucose uptake in skeletal muscle cells and glitazone-like enhancement of adipogenesis.Terpenes isolated from ClFr showed less activity than the total ClFr.
The approval of 10 new CFLR projects to receive funding in 2012, the continuation of funding for 10 other CFLR projects and the designation of three additional high-priority CLFR
projects to be funded out of a separate budget resulted from bipartisan Congressional support.