CMAH - What does CMAH stand for? The Free Dictionary
References in periodicals archive
To test the feasibility of using these knockout cell enrichment approaches for pig fibroblast cells, we used ZFNs targeting CMAH
exon 6 (Figure 1a) and surrogate reporters containing either the eGFP gene alone (eGFP reporter) or eGFP and a truncated H-2Kk surface marker (MACS reporter), whose expression in cells can be recovered by a ZFN-induced frameshift mutation in CMAH
Researchers compared two groups of mice: one with a functional CMAH gene, the other with an altered CMAH gene similar to the human mutation.
However, only mice with the CMAH gene mutation experienced pancreatic beta cell failure - the cells that make and release insulin, a hormone that controls blood sugar levels.