In fact, previous experiments performed at the CMCRC laboratory have shown that a) methanol administered in drinking water, at doses ranging from 20,000 to 500 ppm, induced a statistically significant increase in the incidence of lymphomas/ leukemias in female rats (Soffritti et al.
Moreover, carcinogenic effects for the renal pelvis and ureter, peripheral nerves and proliferative changes of the olfactory epithelium were not observed in the long-term bioassays performed in the same conditions at the CMCRC on methanol, MTBE, or formaldehyde.
