CMP-Neu5AcCytidine 5-Prime-Monophosphate N-Acetylneuraminic Acid Synthetase
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65) KI-8110 has also no effect on CMP-Neu5Ac synthase.
Typically, there is great difficulty and cost associated with creating sialylated products due to the instability of CMP-Neu5Ac synthetase," added contributing author Robert Bayer, group leader of molecular biology and biochemistry at Cytel.
1% of total Sias 51) obtained only directly from nutrition due to an exon deletion/frameshift mutation in the human CMP-Neu5Ac hydroxylase (CMAH) gene encoding CMAH required to transfer an oxygen atom to CMP-Neu5Ac for generation of CMP-Neu5Gc.