Boning, "Noninvasive image derived heart input function for CMRglc
measurements in small animal slow infusion FDG PET studies," Physics in Medicine & Biology, vol.
Kuge et al., 24 hours (i) Ischemic core: 2000  Before and 1, 2, 4, reduced CBF, CMRglc
, 6, and 24 hours and negative TCC.
The abstract of the study concludes with this interesting finding as well: "Consistent with the differential effects on performance, nasal delivered orexin-A produced a more pronounced reversal of sleep deprivation induced changes in brain metabolic activity (CMRglc
) than intravenous orexin-A, These findings provide strong evidence for the effectiveness of intranasal orexin-A in alleviating cognitive deficits produced by loss of sleep."