CMRO2Cerebral Metabolic Rate of O2
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Wang, "Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2) using quantitative susceptibility mapping (QSM)," Magnetic Resonance in Medicine, vol.
Studies have demonstrated that CBF, CMRO2, and CBV values are decreased in the setting of cerebral vasospasm, suggesting dysfunctional vasodilatory compensation in response to ischemia [53].
It is a cerebral vasoconstrictor by stimulating [[alpha].sub.2]b receptors in the cerebral blood vessels with no effect on CMRO2. Dexmedetomidine inhibits the cerebral vasodilatation induced by hypercapnia, thus avoiding increased intracranial pressure and brain bulging.