CNBSSCanadian National Breast Screening Study
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Similarly, the CNBSS I* trial, (14) which randomized women aged 40-49 years either to receive annual mammography and physical breast examination, or to receive a single physical breast examination and instruction on how to conduct self-breast examination, found no reduction in breast cancer mortality after 11 to 16 years of follow-up.
The HIP screening was carried out in the 1960s, while both CNBSS trials were conducted in the 1980s.
Breast cancers were identified through the CNBSS centers and the National Cancer Registry during the 13-year follow-up.