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Related to COHb: carboxyhemoglobinemia, HbCO
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Table 1 Typical COHb levels in various populations Population COHb levels Nonsmokers <1% Smokers <1 % to 9% Pregnancy <5% Hemolytic anemia <5% Urban polluted areas At least 1 % higher than normal COHb: carboxyhemoglobin Source: References 3-5 Table 2 Adverse effects of stimulants and occult CO poisoning Stimulants Occult CO poisoning Nervousness Fatigue Headache Headache Irritability Difficulty thinking Dizziness Dizziness Nausea Nausea Insomnia Insomnia Palpitations Heart pounding CO: carbon monoxide Source: References 1,2,8
Sitting in the cockpit and continuing to breathe even low concentrations of CO means the danger continues to increase as the strong COHb bond causes the concentration in your blood to continue increasing.
The Pearson correlation analysis confirmed a positive relationship between levels of COex and COHb exhaled by the subjects, and FQtot and FQmd, respectively (p < 0.
Blood COHb levels depend on the CO gas concentration in the environment, exposure time, alveolar ventilation, blood volume, and metabolic activity (6).
When CO is inhaled, it binds to hemoglobin to produce COHb, which appropriates the space that normally carries oxygen, thereby depriving the tissues of sufficient oxygen (7).
These alterations were shown in spite of the level of COHb exposure levels being very low (0.
Variables including age, sex, body weight, referral, psychological history, hypotension, GCS, COHb, toxicology screens, laboratory findings, and HBO treatments were analyzed.
1,4) Lab testing for COHb can help narrow the diagnosis.
28 patients were excluded, since they had a COHb level of <10% and been followed up for shorter than 6 hours.
Both arterial and venous COHb and oxygen saturation blood samples were analysed using an Ilex Premium 3000 Blood Gas Analyser.
Factors that influence COHb formation and elimination include CO concentration in air, duration of exposure, and physical activity (CPSC, 2008).