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Corrona and Novartis designed and helped conduct the study.
Corrona's team of biostatisticians and epidemiologists will collaborate with the National MS Society, participating academic and private practice neurologists, as well as supporting pharmaceutical companies.
In 23,327 RA patients included in the CORRONA (Consortium of Rheumatology Researchers of North America) database who were evaluated at 182,201 individual visits between October 2001 and September 2011, the presence of subcutaneous nodules was found to confer a 44% increase in the risk of cardiovascular disease (hazard ratio, 1.44).
National Psoriasis Foundation stated on Monday that Corrona Psoriasis Registry has enrolled its 3,000th psoriasis patient under its collaborative model that integrates the post-approval safety study (PASS) commitments of multiple companies into a single, large-scale registry with multiple drug treatment cohorts.
Additionally, results from the Corrona registry demonstrated that patients with RA who received aTNF agents had a reduced risk of CV events compared with patients who received csDMARDs; however, glucocorticoid use, which maybe a surrogate marker of increased inflammation, was associated with a dose-dependent increase in risk of CV events .
WASHINGTON--Subcutaneous nodules in patients with rheumatoid arthritis signal a significantly increased risk of cardiovascular disease, based on findings from the CORRONA database.
(32) In the Consortium of Rheumatology Researchers of North America (CORRONA) registry who were prescribed methotrexate, TNF antagonists or other disease-modifying anti-rheumatic drugs, low-dose prednisone use overall was not associated with risk of infection.
1421 Cognizant 2235 Community Research 1122 Compass IRB 1311 CompleWare Corporation 427 Compliance Implementation Services (CIS) 2327 COMSYS Life Sciences 1627 Contract Pharma 2234 Copernicus Group IRB 531 Corporate Translations 828 CORRONA 1906 Court Square Group, Inc.
To investigate the relationship between infections and disease activity after adjustment for the effects of drug therapy, analyses on infection rates were done for RA patients from the Consortium of Rheumatology Researchers of North America (CORRONA) database who were on stable doses of disease-modifying antirheumatic drugs, biologic agents, or corticosteroids, according to Dr.
Contracted Research: Abb Vie; Actavis; Amgen; Boehringer Ingelheim; Celgene; Cellceutix; Coherus; Corrona; Dermira; Eli Lilly; Galderma; Glenmark; Janssen; Leo; Merck; Novartis; Novella; Pfizer; Sandoz; Stiefel; Wyeth.
Louis University and her colleagues looked at data from the CORRONA (Consortium of Rheumatology Researchers of North America) registry, a multicenter, longitudinal prospective database in the United States with more than 30,000 patients.
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